Very good point, there are a lot of things to take into consideration. Like what I said about a no till garden, it takes a balance of the three.
The bulk of synthetic salt based nutrients on the market (not specifically marketed / recommend in cannabis growing) have been show to degrade soil quality and cause a few other issues, a lot of these products do not state it and you actually have to do some reading to understand what everything inside them does. And this is why I prefer the organic no till route, especially because I eat a lot of what comes out of my garden.
Edit: yes there are studies that show the opposite, and mentioned in these it comes down to use.
I would just like to add I am no scientist, have never done any testing. Just read stuff and decided to make my own decision.